Reversal by citrate of the iodoacetate and fluoride inhibition of glutamic acid production by Corynebacterium glutamicum.
نویسندگان
چکیده
Citrate reversal of iodoacetate inhibition of glutamate synthesis is nonmetabolic. Reversal of fluoride inhibition is metabolic, occurring only at low Mg concentrations.
منابع مشابه
Fermentative Production of Lysine by Corynebacterium glutamicum from Different Carbon Sources
Production of lysine by Corynebacterium glutamicum (PTCC 1532) from different agricultural by-products (molasses and pulpy waste date) was compared to glucose as raw materials. For this purpose, ammonium sulphate was selected as a constant nitrogen source. The effect of different nitrogen sources was also investigated with glucose as a constant carbon source. The production of L-lysine was exam...
متن کاملThick Juice-Based Production of Amino Acids and Putrescine by Corynebacterium glutamicum
Thick juice (also regarded as syrup) is an intermediate product of sugar processing. It is cheaper than processed sugar and is mainly composed of sucrose. Sucrose is a preferred carbon source of Corynebacterium glutamicum, a workhorse of biotechnology used for million-ton-scale amino acid production. Here, it is shown for C. glutamicum that sugar beet thick juice led to higher growth rates and ...
متن کاملNucleotide sequence, expression and transcriptional analysis of the Corynebacterium glutamicum gltA gene encoding citrate synthase.
Citrate synthase catalyses the initial reaction of the citric acid cycle and can therefore be considered as the rate-controlling enzyme for the entry of substrates into the cycle. In Corynebacterium glutamicum, the specific activity of citrate synthase was found to be independent of the growth substrate and of the growth phase. The enzyme was not affected by NADH or 2-oxoglutarate and was only ...
متن کاملModeling the Fermentative Production of L-glutamic Acid by Corynebacterium Glutamicum in a Batch Bioreactor
The fermentation kinetics of L-glutamic acid by Corynebacterium glutamicum was studied in a batch bioreactor. Mathematical model using the logistic equation for growth, Leudeking-Piret kinetic equation for product formation and Leudeking-Piret like equation for substrate consumption was proposed. Based on the analysis of experimental data followed by computer simulation, the model seemed to pro...
متن کاملProduction of L-glutamic Acid with Corynebacterium glutamicum (NCIM 2168) and Pseudomonas reptilivora (NCIM 2598): A Study on Immobilization and Reusability
BACKGROUND L-glutamic acid is one of the major amino acids that is present in a wide variety of foods. It is mainly used as a food additive and flavor enhancer in the form of sodium salt. Corynebacterium glutamicum (C. glutamicum) is one of the major organisms widely used for glutamic acid production. METHODS The study was dealing with immobilization of C. glutamicum and mixed culture of C. g...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Applied microbiology
دوره 18 2 شماره
صفحات -
تاریخ انتشار 1969